Cialis Super Active (Tadalafil Citrate 20mg)

Everything in our world changes and evolves. Drugs for ED are not an exception. Regardless of availability of huge variety of very effective and credible remedies, the renowned pharmaceutical companies all around the globe work on development of new more efficient, modern and impactful medications, so many men could feel self-confident, strong and mighty. Among the most reliable and demanded remedy with long-lasting action and minimal onset time is Cialis. Cialis Super Active is a branded generic of worldwide popular Cialis with the same active substance, tadalafil. It is issued in the form gel capsules for better absorption in male organism. Cialis Super Active should be taken before planned sexual intercourse regardless of food acceptance. Minimal break between the intake of capsules and starting of coitus is around 10-20 minutes. The effect of Cialis Super Active lasts 36 hours. Even upon the expiration of 35 minutes after sex, the effect will be the same and you may start over. According to medical indications, Cialis Super Active is allowed to be taken only once a day.

Indications to Cialis Super Active Intake

This excellent remedy is a fast-acting medication capable to treat erectile dysfunction (ED), restore potency and guarantee a fully-realized natural sexual intercourse. Cialis Super Active is very effective if a patient fails to achieve and preserve erection sufficient for coitus realization. It is recommended to be taken by people with sexual issues and as a prophylactic remedy as well. Thus, a patient will not only improve the quality of sexual life considerably and experience unbelievably strong sensations, but also protect himself from possible sexual disorders which occur quite often among the representatives of a stronger sex.

Cialis Super Active is quite perfect for men at any age group regardless of the character of sexual disorder. Clinical trials conducted by the best world labs have demonstrated that the intake of this generic doesn’t affect the male reproductive function. After Cialis Super Active gets into organism, tadalafil takes a positive action on blood circulation enhancing blood supply to pelvic organs causing relaxation of smooth muscles cells. This process contributes to appearance of qualitative erection necessary for realization of coitus. This medicine has a long-term action. Therefore, after the intake of a capsule, a man may have as many sexual intercourses within 36 hours as possible. It means that you may have a memorable sex within the course of two days taking pleasure of qualitative and voluptuous experience.

Form of Administration

Cialis Super Active is taken 10-15 minutes before planned sex. Capsules are used along with water. The active substance is compatible with small amount of alcohol. It is not recommended taking capsules along with fat and energy food, since this combination will cause the prolongation of onset time. The medication’s action lasts 36 hours. In order to obtain a desired effect, sexual stimulation is required. Recommended daily dose is 30mg of tadalafil, i.e. one capsule per 24 hours.

Cialis Super Active is issued in a capsulized form, 10 pcs in package. The medication is distinguished by nearly absolute absence of side-effects. In order to have a qualitative effect, a patient should examine the instruction thoroughly before use. The principle restrictions for application are under-age, intolerance to tadalafil, experienced heart or apoplectic attack in past medical history, severe form of renal or hepatic failure. Cialis Super Active is stored out of reach of children, out of reach of direct sunlight. The expiration period is three years from the date of issue.

Health Effects

Cialis Super Active action is based on the principle of enhancement of blood circulation and flow to male sexual organs. It is a quite effective phosphodiesterase type 5 inhibitor (PDE5) which acts along with guanosine monophosphate. Its mode of action is circular. As a result, strong sexual excitement causes emission of nitrogen oxide into blood. Alongside, the process of PDE5 inhibition by Cialis Super Active is under way. It causes improvement of guanosine monophosphate richness in penis cavernous bodies. Right after such chemical reactions, smooth muscle cells get relaxed, and blood is supplied to tense muscles of male sexual organs accordingly. This process causes erection. It should be borne in mind that the medications will not be valid without additional sexual stimulation.

Benefits of CSA Usage

Tadalafil is able to struggle efficiently against any occurrences of impotency and gives possibility to have a fully-realized sex without affecting other essential organs and tissues of organism. Erectile dysfunction is caused by a variety of factors of both physical and psychological origin. Nevertheless, only once a capsule of Cialis Super Active taken, it releases a patient from any issues connected with potency for a long time.

A specialized presentation in capsulized form allows achieving positive result within a short space of time. Cialis Super Active is taken perorally as a traditional medicine taken with a lot of water. Moreover, a medication may be taken either after or before food acceptance and even with small dosage of alcoholic beverages.

Key advantages:

Result occurs within 15 minutes, since gelatinous form of the medicine is easily absorbed in male organism;
Positive useful effects last up to two days;
The drug has minimal restrictions to the intake;
According to customers reviews the medication is well tolerated;
Affordable price: generics cost much cheaper than the originals;
Cialis Super Active is distinguished by its usability due to comfortable presentation form;
Gel capsules are composed of the ingredients which do not irritate mucous tissue of stomach which makes it safe for usage.

Does Generic Cialis Differ from the Original Drug?

Both medications cause relaxation of smooth tissues of penis. Blood stream directed towards male sexual organ gets stronger. Thus, erection is successfully achieved by means of drugs intake along with sexual stimulation. The medicine enables organism to form a strong blood flow for provision of natural erection. Based on the fact that the medicines have one and the same active substance – tadalafil, they have an identical effect.

Generic is a direct analogue of branded medications. It repeats patented medical remedies completely meeting all requirements of international standards. In order to manufacture generics, a company-distributor doesn’t incur losses in comparison with the originals. A customer doesn’t need to pay for brand, whereas efficiency and result remain the same. These are main advantages of generics including Cialis Super Active.

So, what are the advantages of Generic Cialis over its original analogue? The answer is quite simple. The original medication for ED therapy, such as Cialis has a unique chemical composition based on tadalafil. Formula development takes a lot of time: experts should conduct necessary clinical trials, patent specialty, launch it into production, elaborate marketing strategy and so on. All these stages require huge expenses and directly influence the price policy. In comparison with the original drugs, their analogues, such as Cialis Super Active are produced in accordance with ready developed formula (only the auxiliary agents differ). This fact decreases and cheapens the process of medications issue.

As a result the substitutes of branded remedies differ according to the following factors:

Low cost along with identical efficiency and safety;
Availability for men who have an average level of earnings;
Great variety of presentation forms and dosages.

Where to Buy Cialis Super Active?

Cialis Super Active may be purchased from online pharmacy at much lower price. Thus, a patient not only reduces expenses on sexual pleasure, but also acquires a wonderful remedy for ED treatment. You should never give up if you came across sexual issues. Cialis Super Active will help you to forget about misfortunes and enjoy a high-quality and sound sex. It is stated by numerous positive reviews from men throughout the world who overcame sexual frustration and returned self-confidence once and for all.

Counter-Indications

Since this drug is well tolerated by men in comparison with Viagra’s sildenafil, the list of contraindications is shorter.

A patient must not take Cialis Super Active in the following cases:

age under 18 years;
cardiac angina (comprising occurring during sexual intercourse);
rehabilitation period after heart or apoplectic attack and myocardial infarction (within the last three months);
idiosyncrasy to the drug components;
severe renal (CK 31-50 ml/min) and hepatic disorders (CK 30 ml/min);
vascular hypotension (arterial blood pressure is lower than 90/50 mm of mercury);
chronic or acquired cardiac failure within the last six months;
deformation of penis (congenital or acquired);
underlying risk for priapism;
simultaneous intake with some drugs, such as nitrates, alpha blockers.

Adverse effect may be caused by simultaneous intake with grapefruit or grapefruit juice. Consult a specialist the possibility to take Cialis Super Active with this fruit.

Incompatible Drugs with Cialis Super Active

No way can Cialis Super Active be co-administered with:

particular antibiotics;
nitrate-containing medications;
alpha adrenoceptors blockers;
nitrogen donors;
anti-depressants.

Possible and Hazardous Interactions

Inhibitors of cytochrome P450 mainly with participation of CYP3 A4 may enhance tadalafil’s action.
Ketoconazole (400mg daily) is a selective and strong inhibitor of CYP3 A4. It enhances tadalafil AUC by 312% and Cmax by 22% in comparison with tadalafil in the same dosage. Ketoconazole (200mg daily) enhances tadalafil AUC by 107% and Cmax by 15% in comparison with tadalafil in the same dosage.
HIV protease inhibitor – ritonavir (200mg twice a day) is CYP3 A4, CYP2 C9, CYP2 C19 and CYP2 D6 inhibitor. It enhances tadalafil AUC by 124% and without any influence on Cmax. Although other particular interactions were not examined, it may be assumed that HIV protease inhibitors may increase the efficiency of Cialis Super Active.
Other cytochrome P450 inhibitors. Although particular interactions were not observed it may be assumed that CYP3 A4 inhibitors, such as erythromycin, itraconasole and grapefruit juice may increase tadalafil exposition.
Cytochrome P450 inducers may decrease the effect of Cialis Super Active.
Rifampicin (600mg per day) enhances tadalafil AUC by 88% and Cmax by 46% in comparison with tadalafil in the same dosage. Although particular interactions were not observed it may be assumed that CYP3 A4 inhibitors, such as carbamazepine, phenytoin, and phenobarbital may decrease tadalafil exposition. Correction of dosage is not required.
Gastro-intestinal remedies.
H2-antihistaminic agents. Increase of pH in stomach in case of nizatidine intake doesn’t have any significant impact on pharmacokinetics of Cialis Super Active.
Simultaneous intake of tadalafil with antacids decreases the absorption rate without changing of tadalafil AUC.
Alcohol and PDE5 inhibitors including tadalafil are weak system vasodilators. In case of their combination, hypotensive effect of each composition may enhance. Large amount of alcohol in combination with tadalafil may increase the possibility of postural signs and symptoms including increase of cardiac rate, decrease of arterial blood pressure, vertigo and headache.
Anti-hypertensive medications. PDE5 inhibitors including tadalafil are system vasodilators.
Alpha-adrenergic blocking agents.
While its co-administration with 20mg of tadalafil by healthy volunteers, a considerable increase of hypotensive effect of doxazosin was observed.
The clinical trial has shown that healthy volunteers did not have considerable arterial blood pressure drop after co-administration of these two drugs.
Acetylsalicylic acid. Tadalafil doesn’t potentiate the increase of time of bleeding caused by acetylsalicylic acid.

Possible Side-Effects

Medicines for potency improvement may cause adverse medical consequences and Cialis Super Active is not an exception. Nevertheless side-effects disappear fast. Very often they occur in the form of mild headaches, stuffiness in nose, slight vertigo. In order to avoid the appearance of undesired effects, the remedy should be taken not more than 1 capsule per day. Cialis Super Active in capsule form doesn’t cause allergic reactions. Anyway, it should be taken carefully in case of congenital or acquired penis deformations, acute hepatic failure or severe cardiac diseases. Besides, medical experts note that tadalafil may not be accepted by organism of 1-2% of patients. In case a patient experiences side-effects, he should consult a specialist.

Among undesired effects, headaches and dyspepsia are the most frequently-met which is expressed in percentage ratio – 11,7%. Many research studies of side-effects have shown that the majority of side-effects connected with Cialis Super Active intake were mostly harmless. Their influence decreased after continued intake of the medicine.

Other standard adverse effects of capsules included backache, myalgia, rhinitis, and blushing. Very rarely, a patient may feel eyelid swelling, sudden pain in eyes area, as well as vertigo. In case you have troubles with side-effects, you may be recommended trying the medications of analogous action, such as Viagra (sildenafil) or Levitra (vardenafil).

Overdose

Symptoms: in case of prescription for healthy volunteers the one-time dosage up to 500mg and patients suffering from erectile dysfunction the many-time dosage up to 1000mg, the adverse effects were the same as in case of small dosage intake. Treatment: standard supporting treatment. Hemodialysis is insignificantly effective for elimination of tadalafil.

Storage Requirements

Cialis Super Active should be stored in compliance with the following rules:

Keep in dark place and do not store above 30 degrees Celsius;
Do not break damage to the original package of the drug;
Place Cialis in safe place away from reach of children or animals.

Disclaimer

The information uncovered in this article has been compiled with the educational purposes only. The team of authors provides the fact checking before posting any kind of information on this website. But the site’s administration does not guarantee correctness and/or update status of all contents in this article. This article can be taken as a guidance for self-treatment. Only licensed and professional healthcare specialist can diagnose and treat patients considering the personal symptoms in each particular case.

Cialis Super Active (Tadalafil): Administration, Benefits, Interaction